Infections-and-Pregnancy Books

A great read about a monumental moment in the history of medicine. Originally entitled "Houses of Death," the book is more a historical record of the diagnosis of childbed fever than a biography of Semmelweis. Well written and intended for a general audience, the Carters unfortunately found the wrong publisher for the book. If you have any interest in the history of medicine at all, this is a must read book.

This book, first of all, consists of a brief introduction (2 pages), a brief Preface (2 pages), and six chapters in the order of which three are devoted to initial medical and scientific background, two are focused on Ignaz Semmelweis himself as well as his discovery, while the final two involve a discussion of Mayrhofer's discovery (Mayrhofer was Semmelweis's progeny, so to speak) and a contemporary look at the growing threat of virulent forms of streptococci, the bacteria now known to be the cause for the so-called childbed fever or, more accurately, puerperal fever.

As a scientific biography of the life and work of Ignaz Semmelweis, the heart of the book belongs to Chapters 3 and 4 where the authors discuss Semmelweis's struggles to prevent childbed fever and to know its cause while also giving attention to his theory of causation. For reasons the authors make tragically clear, Ignaz Semmelweis failed to have his work and discovery be immediately accepted, and he died ignobly, having been used, as a political pawn by those in power who believed in his discovery and work, and, simultaneously abused, by yet others in power who did not believe in his discovery and could, and, in fact, did refuse him work as well as respect.

By and large, this book is intended for a popular audience and is charmingly, engagingly, and dramatically written, making "clear exactly" why Ignaz Semmelweis, a once-head resident of obstetrics in 1846 Vienna, was and remains an important figure in medical science - not just to pregnant women and neonates then and now and not just to the now widely accepted practice of antiseptics, but as well to the theoretical development of modern medicine in the early 19th and 20th centuries for the authors show distinctively how Semmelweis, as an innovator, was among the most important mid-19th century scientific figures for defining diseases in such a way that each disease has only one specific cause, a way of thinking that we take for granted today but was completely revolutionary in the mid-1800s.

The charm of this lucidly written work comes from a pleasant knack for accurate historical detail of the time-period, as if observed from a fresh, eye-witness account: "In the nineteenth century, Vaci uta was an important shopping street . . . The building [in which Semmelweis lived] encloses a quiet courtyard from which an ancient well-worn circular marble stairway ascends to the third floor . . ." or "The General Hospital occupies a system of buildings that surrounds a dozen large rectangular courtyards arranged like an irregular checkerboard. The courtyards contain gardens, shady trees, walks, and occasional statutes of prominent persons who have been associated with Viennese medicine."

What is touching and essentially dramatic about this work comes from the well-organized narrative sweep of events the authors orchestrate in keeping with a near-mythic story-line of a young and enterprising man who, as a living protagonist, heroically emerges from a miserable hospital setting, really a house of death (the real and intended name for this book, according to the authors' Introduction, was "House of Death"), to become someone who pits himself against a dreadful antagonist, the killer disease then known as "childbed fever", and, remarkably, in the end, defeats it (or, at least, renders it significantly impotent), while, simultaneously, giving the world a universal, necessary gift, much like Prometheus is said to have given mankind fire.

What is unique about this particular biography, the facts of which nearly every student of medical history apparently already knows, is that, as a popular primer, it satisfies the reader's intellectual curiosity (for "Why?") without ruining the narrative pace for those readers who simply might just want "a good read." It also invents no detail where historical facts are unavailable just merely to keep progress with a strong narrative. The authors stay unflinchingly true to the historical record and yet create no bar to the flow of the story.

The last chapter (Chapter 6) is a bit disconcerting but provocative overall. While this chapter might feasibly have been reduced to an extended footnote after Chapter 5, "Mayrhofer's Discovery," on the one hand, or might have been labeled as an Appendix, on the other, thus transforming the chapter in such a way as to make it more consistent in tone as a popular primer, it contains noteworthy contemporary analyses of streptococci today, first as they relate to puerperal fever, but secondly, and perhaps more importantly, to the threat of the virulent growth of streptococci in the near-future, scarily yet prophetically hinting at events (not known in 2005 when the book was published, but which) we now know in 2007 as "the Superbug" (MRSA) for which there is abundant horrific evidence presently in Baltimore, Maryland.

This last chapter calls out for even greater understanding of streptococci and caution in dealing with it, and, in its own understated but emphatically philosophical way, it ultimately illustrates the idea that the philosophy of science is not a mere Ivory Tower enterprise; it is a highly practical project, one with life-or-death or real consequences.

This is a wonderful book and highly recommended to everyone. A couple of minor quibbles are appropriate at this point, and the first has to do with the price. It ought to be more affordable for its intended target audience. $24 (plus tax) for a paperback is steep. Secondly, since this work is largely a republication of an earlier 1995 hardback but with an Introduction newly added, the early error of repeating Semmelweis's age at death as being "forty-two" (as it was printed in the original Preface) ought to have been fixed before republishing. That having been said, to find the footnotes arranged at the end of each chapter rather than at the end of the book was itself a real joy as it made reading each chapter easy and eliminated the drudgery of flipping back and forth between pages to points of distraction. Reading this short book was an emotional as well as intellectual delight. May it find a broad audience (and perhaps a less technical publisher).

The first edition of this book had won The American Medical Writer's Award for Best Multi-Authored Text. This is a Third Edition. There is now a 4th Edtion, published in 1999, also available.

Fourth Edition (4th) is available.

When I have questions about matters medical, friends recommend books that are scholarly, and written in plain English, so I can understand.

This is that type of book, and its being published in the 6th edition says a lot.

Reading on medical diseases can normally put me to sleep. When it's on a medical subject of interest,say on something a friend is experiencing, this book aces out any babble I'd find by "googling" and reading whatever dozen conflicting "self proclaimed experts" spout.

This is what the Docs rely on to save lives, has been in print for 30 years with updates- that's more than a good enough recommendation for me.

This book is not intended as a light reader into the relatively new field of fetal origins of adult disease. Those with a medical (nurses, MA's, doctors) or scientific (college students) background will find it to be a challenge to many of the traditional notions of how we stay healthy and become ill. This book goes into the scientific findings which have lead many researchers world wide to focus on the intrauterine environment as the basis for many adult diseases such as diabetes and heart disease. Dr. Barker is not only the author of the book, but is also the scientist that made most of the discoveries written about in the book. It was his research that has started off this incredible field of research. As a MD/PhD student I found it readable and very pertinent to medical care in the 21st century. Those involved in patient care, especially the care of children, owe it to their patients to learn more in this area.